Human abdominal abscess caused by Necropsobacter rosorum and tips for its identification: A case report.

Abstract

Necropsobacter rosorum is a gram-negative facultative anaerobe, which was reclassified from the family Pasteurellaceae in 2011. It has been detected in the gastrointestinal and respiratory tracts of mammals; however, reports of infection in humans are scarce. We report a case of an abdominal abscess in which N. rosorum was detected; it was successfully treated with drainage and antimicrobial therapy. Routine laboratory testing such as matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and an identification system using biochemical phenotypes could not identify N. rosorum. Instead, it was misidentified as other Pasteurellaceae species, including Aggregatibacter spp. or Pasteurella spp. Sequencing of 16S rRNA was required to identify N. rosorum. We suggest the application of simple methods, such as indole production, oxidase, and catalase tests, to differentiate N. rosorum from genetically similar species.

• Authors: Chihiro Jin, Yuji Wakimoto, Mahoko Ikeda, Yuki Ohama, Motonari Ri, Hiroharu Yamashita, Amato Ohtani, Marie Yamashita, Takayuki Shinohara, Daisuke Jubishi, Yoshiaki Kanno, Koh Okamoto, Yoshimi Higurashi, Sohei Harada, Shu Okugawa, Yasuyuki Seto, Kyoji Moriya
• Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (J Infect Chemother) Vol. 28 Issue 6 Pg. 833-835 (Jun 2022) ISSN: 1437-7780 [Electronic] Netherlands
• PMID: 35190256 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2022 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

Chemical References

• RNA, Ribosomal, 16S

Topics

• Abdominal Abscess (diagnosis)
• Animals
• Humans
• Mammals (genetics)
• Pasteurellaceae (genetics)
• RNA, Ribosomal, 16S (genetics)
• Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization (methods)