Hypersensitivity reactions to vaccines in children: from measles to SARS-CoV-2.

Abstract

Allergic individuals at risk for hypersensitivity reactions to measles vaccine marketed for a long time are well established. On the other hand, risk factors for hypersensitivity reactions to the new mRNA COVID-19 vaccines currently include a history of allergy, allergy to excipient of the vaccine, or hypersensitivity reactions to the first dose of COVID-19 vaccine. In the last two cases, the recipient should be assessed by an allergist before vaccination to share a decision on the choice of vaccination. Studies on skin testing accuracy and desensitization protocols to the COVID-19 vaccines and the efficacy of potential alternatives in patients with confirmed hypersensitivity reactions to the first COVID-19 vaccine are necessary to improve the safety of COVID-19 vaccines.

• Authors: Carlo Caffarelli, Lucia Liotti, Annamaria Bianchi, Paolo Bottau, Silvia Caimmi, Giuseppe Crisafulli, Fabrizio Franceschini, Claudia Paglialunga, Francesca Saretta, Francesca Mori
• Journal: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (Pediatr Allergy Immunol) Vol. 33 Suppl 27 Pg. 58-60 (01 2022) ISSN: 1399-3038 [Electronic] England
• PMID: 35080320 (Publication Type: Journal Article)
• Copyright: © 2022 The Authors. Pediatric Allergy and Immunology published by European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd.

Chemical References

• COVID-19 Vaccines
• Vaccines

Topics

• COVID-19
• COVID-19 Vaccines
• Child
• Humans
• Hypersensitivity (etiology)
• Measles (prevention & control)
• SARS-CoV-2
• Vaccination (adverse effects)
• Vaccines