[Immune thrombocytopenia associated with Kimura's disease].

Abstract

In this study, we report a rare case of immune thrombocytopenic purpura (ITP) associated with the worsening of Kimura's disease. A 47-year-old Japanese man with a pruritic rash and swollen inguinal lymph nodes was diagnosed with Kimura's disease on performing a right inguinal lymph node biopsy. Thrombocytopenia ensued after the diagnosis of Kimura's disease, and fluctuations in the platelet count were observed along with the pathology of Kimura's disease. The platelet count fluctuated repeatedly with the relapse of Kimura's disease and a diagnosis of a combination of Kimura's disease and ITP was made through lymph node regeneration and bone marrow examination. Treatment with prednisolone (1 mg/kg/day) was initiated for Kimura's disease and ITP, and lymphadenopathy and platelet count improved promptly. Since then, the dose of prednisolone has been gradually reduced, and the disease status of both Kimura's disease and ITP has been controlled.

• Authors: Shintaro Oga, Oju Katayama, Yuko Ogata, Yuichi Nakazono
• Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology (Rinsho Ketsueki) Vol. 62 Issue 12 Pg. 1666-1671 ( 2021) ISSN: 0485-1439 [Print] Japan
• PMID: 35022334 (Publication Type: Case Reports, Journal Article)

Topics

• Angiolymphoid Hyperplasia with Eosinophilia (complications, diagnosis, drug therapy)
• Humans
• Kimura Disease
• Lymphadenopathy
• Male
• Middle Aged
• Purpura, Thrombocytopenic, Idiopathic (complications, diagnosis, drug therapy)
• Thrombocytopenia