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The impact of invisible-spreaders on COVID-19 transmission and work resumption.

Abstract
The global impact of coronavirus disease 2019 (COVID-19) is unprecedented, and many control and prevention measures have been implemented to test for and trace COVID-19. However, invisible-spreaders, who are associated with nucleic acid detection and asymptomatic infections, have received insufficient attention in the current COVID-19 control efforts. In this paper, we analyze the time series infection data for Italy, Germany, Brazil, India and Sweden since the first wave outbreak to address the following issues through a series of experiments. We conclude that: 1) As of June 1, 2020, the proportion of invisible-spreaders is close to 0.4% in Sweden, 0.8% in early Italy and Germany, and 0.4% in the middle and late stages. However, in Brazil and India, the proportion still shows a gradual upward trend; 2) During the spread of this pandemic, even a slight increase in the proportion of invisible-spreaders could have large implications for the health of the community; and 3) On resuming work, the pandemic intervention measures will be relaxed, and invisible-spreaders will cause a new round of outbreaks.
AuthorsChao Wu, Cong Xu, Feng Mao, Xiaolin Xu, Chan Zhang
JournalPloS one (PLoS One) Vol. 17 Issue 1 Pg. e0252994 ( 2022) ISSN: 1932-6203 [Electronic] United States
PMID35020722 (Publication Type: Journal Article)
Topics
  • Asymptomatic Infections (epidemiology)
  • Brazil (epidemiology)
  • COVID-19 (diagnosis, epidemiology, transmission, virology)
  • Germany (epidemiology)
  • Humans
  • India (epidemiology)
  • Italy (epidemiology)
  • Models, Theoretical
  • Pandemics
  • SARS-CoV-2 (isolation & purification)
  • Sweden (epidemiology)

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