Abstract | OBJECTIVES: METHODS: RESULTS:
NAFLD was diagnosed in 31 children. Total FA concentration was significantly higher (P < 0.01) in all obese children as well as in obese children with NAFLD compared with controls. In children with NAFLD, a significant, positive correlation was found between total FA concentration and cholesterol (R = 0.47, P < 0.01), triacylglycerols (R = 0.78, P < 0.001), and insulin (R = 0.45, P < 0.011). In a group of children with obesity, TILC correlated positively with saturated FA concentration (R = 0.23, P < 0.05). CONCLUSION: Data from the present study do support the hypothesis that FAs are potentially involved in the pathogenesis of NAFLD in children with obesity.
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Authors | Natalia Kopiczko, Anna Bobrus-Chociej, Ewa Harasim-Symbor, Eugeniusz Tarasów, Małgorzata Wojtkowska, Adrian Chabowski, Dariusz M Lebensztejn |
Journal | Nutrition (Burbank, Los Angeles County, Calif.)
(Nutrition)
Vol. 94
Pg. 111541
(02 2022)
ISSN: 1873-1244 [Electronic] United States |
PMID | 34974284
(Publication Type: Journal Article)
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Copyright | Copyright © 2021 Elsevier Inc. All rights reserved. |
Chemical References |
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Topics |
- Child
- Fatty Acids
(metabolism)
- Humans
- Insulin Resistance
- Liver
(diagnostic imaging, metabolism)
- Non-alcoholic Fatty Liver Disease
- Pediatric Obesity
(complications)
- Prospective Studies
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