[Imipenem/cilastatin sodium in the treatment of obstetric and gynecologic infections].

Abstract

Imipenem/cilastatin sodium (MK-0787/MK-0791), a carbapenem antibiotic and a dehydropeptidase-I inhibitor, was administered at a dose of 500 mg/500 mg twice a day for 5 days for the treatment of obstetric and gynecologic infections. A total of 10 patients was evaluated, and the clinical results were rated as excellent in 1, good in 7 and poor in 2 patients. As a side effect, rash was observed in 1 patient but it disappeared by the third day after the treatment was discontinued. No abnormal laboratory findings were observed in our study.

• Authors: F Doko
• Journal: The Japanese journal of antibiotics (Jpn J Antibiot) Vol. 39 Issue 5 Pg. 1427-31 (May 1986) ISSN: 0368-2781 [Print] Japan
• PMID: 3463788 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Cyclopropanes
• Drug Combinations
• Thienamycins
• Cilastatin
• Imipenem

Topics

• Adult
• Aged
• Bacterial Infections (drug therapy)
• Cilastatin
• Cyclopropanes (administration & dosage)
• Drug Combinations
• Female
• Genital Diseases, Female (drug therapy)
• Humans
• Imipenem
• Middle Aged
• Thienamycins (administration & dosage)