Toxicity of carbon ion radiotherapy and immune checkpoint inhibitors in advanced melanoma.

Abstract

We analyzed CTCAE adverse events of sequential Carbon Ion radiotherapy (CIRT) and immune checkpoint inhibitors (ICIs) in advanced melanoma patients. The frequencies of early and late adverse events (AEs) were 100% and 82% of patients, respectively. The frequency of G3+ AEs was in line with the literature.

• Authors: Stefano Cavalieri, Sara Ronchi, Amelia Barcellini, Maria Bonora, Barbara Vischioni, Viviana Vitolo, Riccardo Villa, Michele Del Vecchio, Lisa Licitra, Ester Orlandi
• Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology (Radiother Oncol) Vol. 164 Pg. 1-5 (11 2021) ISSN: 1879-0887 [Electronic] Ireland
• PMID: 34506831 (Publication Type: Journal Article)
• Copyright: Copyright © 2021 Elsevier B.V. All rights reserved.

Chemical References

• Immune Checkpoint Inhibitors

Topics

• Heavy Ion Radiotherapy (adverse effects)
• Humans
• Immune Checkpoint Inhibitors
• Melanoma (drug therapy)