Abstract | BACKGROUND: OBJECTIVES: The objective of this study was to scrutinize the surgical procedure and perioperative patient management with emphasis on perioperative morbidity and local tumor control. METHODS: In 2014, a standardized EPD and HITOC procedure was implemented at the Thoraxklinik Heidelberg. This retrospective analysis included clinical data of consecutive patients with pleural mesothelioma and pleural metastasized malignancies treated by EPD and HITOC. The surgical procedure, perioperative management, lung function data, and progression-free survival (PFS) were analyzed. RESULTS: CONCLUSION: Combining EPD with HITOC can be performed in patients with either pleural mesothelioma or pleural metastases resulting in low perioperative morbidity and mortality as well as remarkable local tumor control.
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Authors | Laura V Klotz, Christiane Gruenewald, Elena L Bulut, Florian Eichhorn, Michael Thomas, Rajiv Shah, Mark Kriegsmann, Werner Schmidt, Othmar Kofler, Hauke Winter, Martin E Eichhorn |
Journal | Respiration; international review of thoracic diseases
(Respiration)
2021
Vol. 100
Issue 12
Pg. 1165-1173
ISSN: 1423-0356 [Electronic] Switzerland |
PMID | 34384085
(Publication Type: Journal Article)
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Copyright | © 2021 S. Karger AG, Basel. |
Topics |
- Carcinoma, Non-Small-Cell Lung
- Combined Modality Therapy
- Cytoreduction Surgical Procedures
- Humans
- Hyperthermia, Induced
- Lung Neoplasms
(therapy)
- Mesothelioma
(surgery)
- Mesothelioma, Malignant
- Neoplasm Recurrence, Local
- Pleural Neoplasms
(surgery)
- Retrospective Studies
- Thoracic Surgery
- Thymus Neoplasms
(pathology)
- Treatment Outcome
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