Superficial Needling Acupuncture vs Sham Acupuncture for Knee Osteoarthritis: A Randomized Controlled Trial.

Abstract

BACKGROUND:

Acupuncture has been an alternative approach for pain management, but trial evidence is conflicting.

METHODS:

Eighty-six patients with knee osteoarthritis were randomly assigned in a 1:1 ratio from June 14, 2017, to January 20, 2019, to receive either superficial needling acupuncture treatment or sham acupuncture for 10 sessions over a 4-week treatment period, followed by a 6-week follow-up period. The primary outcome was the change of pain intensity at week 4 measured using a 100-mm visual analogue scale. Secondary outcomes included the Western Ontario and McMaster Universities Osteoarthritis Index and 36-Item Short Form Health Survey.

RESULTS:

At the end of the 4-week treatment period, mean changes in the visual analogue scale were -30.8 (95% confidence interval [CI], -38.2 to -23.0; p <.001) in the acupuncture group and -26.7 (95% CI, -34.4 to -18.8; P <.001) in the sham group. The difference between the acupuncture group and the sham group was -4.1 (95% CI, -14.4 to 6.2; P = 0.431). At week 10, the difference between the groups was -2.2 (95% CI, -13.1 to 8.8; P =0.699). There was no statistically significant difference in Western Ontario and McMaster Universities Osteoarthritis Index subscores (pain, stiffness, and physical function) and 36-Item Short Form Health Survey-related outcomes across groups from weeks 2 to 10. The incidence of treatment-related adverse events was 4.4% in the acupuncture group and 0.8% in the sham acupuncture group. All adverse events were classified as mild.

CONCLUSION:

Acupuncture for 4 weeks is not superior to non-penetrating sham acupuncture. The current study cannot confirm that superficial acupuncture has efficacy for the treatment of knee osteoarthritis.

• Authors: Wing Chung Lam, Kwok Yin Au, Zongshi Qin, Fung Man Wu, Chiu On Chong, Fei Jiang, Yue He, Bacon Fung Leung Ng, Wing-Fai Yeung, Lixing Lao, Haiyong Chen
• Journal: The American journal of medicine (Am J Med) Vol. 134 Issue 10 Pg. 1286-1294.e2 (10 2021) ISSN: 1555-7162 [Electronic] United States
• PMID: 34126097 (Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2021 Elsevier Inc. All rights reserved.

Topics

• Acupuncture Therapy (methods)
• Disability Evaluation
• Female
• Hong Kong
• Humans
• Male
• Middle Aged
• Osteoarthritis, Knee (therapy)
• Pain Management
• Pain Measurement