Abstract | INTRODUCTION: METHODS: Children 0-18 years-old in the Extracorporeal Life Support Organization (ELSO) Registry with a primary or secondary diagnosis of WS, SVAS, PAS, or PAS were included. RESULTS: Included were 50 WS children and 1222 non-WS children with similar cardiac diagnoses. ECMO use increased over time in both groups (p = 0.93), with most cases occurring in the current era. WS children were younger (p = 0.004), weighed less (p = 0.048), had a pulmonary indication for ECMO (50% vs 10%, p < 0.001), and were placed more on high frequency ventilation (p < 0.001) than non-WS patients. Despite reporting a respiratory indication, most (84%) WS patients were placed on VA-ECMO. There were no significant differences between the two groups in terms of pre-ECMO cardiac arrest, ECMO duration, or reason for ECMO discontinuation. Both groups had a mortality rate of 48% (p = 1.00). No risk factors for WS mortality were identified.
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Authors | Amarilis Martin, Peter T Rycus, Ahmad Farooqi, John Dentel, Katherine Cashen |
Journal | Perfusion
(Perfusion)
Vol. 37
Issue 4
Pg. 359-366
(05 2022)
ISSN: 1477-111X [Electronic] England |
PMID | 33653195
(Publication Type: Journal Article, Review)
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Topics |
- Adolescent
- Child
- Child, Preschool
- Extracorporeal Membrane Oxygenation
(methods)
- Hospital Mortality
- Humans
- Infant
- Infant, Newborn
- Registries
- Retrospective Studies
- Williams Syndrome
(etiology, therapy)
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