Abstract | BACKGROUND:
Heart failure (HF) hospitalizations remains a significant burden on the health care system. Stimulants including cocaine, amphetamine and its derivatives are amongst the most used illegal substances in the United States. The information regarding stimulant-related HF hospitalizations is scarce. We sought to evaluate the characteristics and trends of stimulant-related HF hospitalizations in the United States and their associated outcomes and resource utilization. METHODS: Using the National Inpatient Sample (NIS), we identified patients with a primary diagnosis of HF hospitalization. These hospitalizations were further divided into those with and without a concomitant diagnosis of stimulant ( cocaine or amphetamine) dependence or abuse. Survey specific techniques were employed to compare trends in baseline characteristics, complications, procedures, outcomes and resource utilization between the two cohorts. RESULTS: We identified 9,932,753 hospitalizations (weighted) with a primary diagnosis of heart failure, of those 138,438 (1.39%) had a diagnosis of active stimulant use. The proportion of stimulant-related HF hospitalization is on the rise (1.1% to 1.9%). Stimulant-related HF hospitalization was highest amongst age group 30-39 years and 7.9% of HF hospitalizations in this age group were due to stimulant use. The proportion of stimulant-related HF hospitalization for the White and Hispanic race has doubled from 2008 to 2017. Stimulant-related HF hospitalization is associated with increased incidence of in-hospital complications like cardiogenic shock, acute kidney injury and ventricular tachycardia. These patients have more than 7-fold higher discharge against medical advice. CONCLUSIONS: Stimulant-related HF hospitalizations have been increasing. It is associate with significant morbidity burden and health care utilization.
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Authors | Suchith Shetty, Aaqib H Malik, Abbas Ali, Ying Chi Yang, Alexandros Briasoulis, Paulino Alvarez |
Journal | International journal of cardiology
(Int J Cardiol)
Vol. 331
Pg. 158-163
(05 15 2021)
ISSN: 1874-1754 [Electronic] Netherlands |
PMID | 33535075
(Publication Type: Journal Article)
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Copyright | Copyright © 2021. Published by Elsevier B.V. |
Topics |
- Adult
- Heart Failure
(diagnosis, drug therapy, epidemiology)
- Hispanic or Latino
- Hospitalization
- Humans
- Inpatients
- United States
(epidemiology)
- White People
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