Abstract | AIM: METHODS: We analyzed consecutive gastric cancer patients who were randomly assigned to undergo Billroth I or Roux-en-Y reconstruction after distal gastrectomy. We evaluated body weight change, nutritional status, late complications, quality of life (QOL) using the European Organization for Research and Treatment of Cancer Core QOL Questionnaire, and dysfunction using the Dysfunction After Upper Gastrointestinal Surgery for Cancer, 5 years after surgery. RESULTS: A total of 228 patients (Billroth I = 105; Roux-en-Y = 123) were eligible for efficacy analyses in this study. Body weight loss 5 years after surgery did not differ significantly between the Billroth I and Roux-en-Y groups (10.0% ± 7.9% and 9.6% ± 8.4%, respectively; P = .70). There were no significant differences in other aspects of nutritional status between the two groups. Reflux esophagitis occurred in 19.0% of the patients in the Billroth I group vs 4.9% in the Roux-en-Y group (P = .002). Regarding QOL, Billroth I was significantly inferior to Roux-en-Y on the diarrhea scale ( Billroth I: 28.6, Roux-en-Y: 16.0; P = .047). Regarding dysfunction, no score differed significantly between the two groups. CONCLUSIONS:
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Authors | Yutaka Kimura, Jota Mikami, Makoto Yamasaki, Motohiro Hirao, Hiroshi Imamura, Junya Fujita, Atsushi Takeno, Jin Matsuyama, Kentaro Kishi, Takafumi Hirao, Hiroki Fukunaga, Koichi Demura, Yukinori Kurokawa, Shuji Takiguchi, Hidetoshi Eguchi, Yuichiro Doki |
Journal | Annals of gastroenterological surgery
(Ann Gastroenterol Surg)
Vol. 5
Issue 1
Pg. 93-101
(Jan 2021)
ISSN: 2475-0328 [Electronic] Japan |
PMID | 33532685
(Publication Type: Journal Article)
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Copyright | © 2020 The Authors. Annals of Gastroenterological Surgery published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Society of Gastroenterological Surgery. |