Abstract | BACKGROUND:
Minocycline is a tetracycline antibiotic that is widely used to treat infections and is a first-line oral antibiotic in the treatment of moderate to severe inflammatory acne. Although it has high efficacy, several adverse reactions, including life-threatening ones, have been reported in association with its use. OBJECTIVE: To identify all the potential adverse reactions due to minocycline and analyze them in terms of the number of cases reported so far, salient features, severity and clinical outcome. METHODS: Comprehensive PubMed search of English and non-English literature for case reports of adverse reactions to minocycline was conducted. RESULTS: CONCLUSION: In view of the evident potential of minocycline to cause long-lasting and severe adverse effects, significant morbidity and even mortality, it should be prescribed with caution in the first-line treatment for moderate to severe acne.
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Authors | Maria Rose Dominic |
Journal | Current drug safety
(Curr Drug Saf)
Vol. 16
Issue 3
Pg. 309-321
( 2021)
ISSN: 2212-3911 [Electronic] United Arab Emirates |
PMID | 33494681
(Publication Type: Journal Article, Review)
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Copyright | Copyright© Bentham Science Publishers; For any queries, please email at [email protected]. |
Chemical References |
- Anti-Bacterial Agents
- Minocycline
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Topics |
- Acne Vulgaris
(diagnosis, drug therapy)
- Anti-Bacterial Agents
(adverse effects)
- Humans
- Minocycline
(adverse effects)
- Pulmonary Eosinophilia
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