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Wound Healing Treatments After Ablative Laser Skin Resurfacing: A Review.

Abstract
Laser resurfacing has progressed since the 1980s to treat a variety of medical and aesthetic indications with ever-evolving safety parameters. While laser technology has evolved to provide a more favorable safety profile and decrease wound healing time, advances in post-procedure healing agents have also helped to mitigate adverse effects, such as persistent erythema, dyspigmentation, acneiform eruptions, dermatitis, infections, and scarring. We reviewed the evidence of growth factors, stem cells, silicone and silicone polymers, botanical based treatments, fatty acids, probiotics, and closed dressings on post-ablative laser skin resurfacing. All reviewed agents demonstrated some evidence in improving post-procedure outcomes, albeit mixed in many cases. Additionally, these studies contain small numbers of participants, vary in type, strength, and clinical indication for which the resurfacing laser was used, and have differing postprocedural evaluation protocols and assessments. This highlights a need for standardization of clinical studies and the importance of choosing an optimal postprocedural skincare plan depending on every unique clinical scenario. J Drugs Dermatol. 2020;19(11):1050-1055. doi:10.36849/JDD.2020.5386.
AuthorsHayley Leight-Dunn, Margot Chima, Elika Hoss
JournalJournal of drugs in dermatology : JDD (J Drugs Dermatol) Vol. 19 Issue 11 Pg. 1050-1055 (Nov 01 2020) ISSN: 1545-9616 [Print] United States
PMID33196756 (Publication Type: Journal Article, Review)
Chemical References
  • Intercellular Signaling Peptides and Proteins
  • Silicones
Topics
  • Acneiform Eruptions (etiology, therapy)
  • Cicatrix (etiology, therapy)
  • Clinical Trials as Topic
  • Cosmetic Techniques (adverse effects)
  • Dermatitis (etiology, therapy)
  • Erythema (etiology, therapy)
  • Esthetics
  • Humans
  • Intercellular Signaling Peptides and Proteins (administration & dosage)
  • Laser Therapy (adverse effects)
  • Pigmentation Disorders (etiology, therapy)
  • Postoperative Complications (etiology, therapy)
  • Probiotics (administration & dosage)
  • Silicones (administration & dosage)
  • Skin Aging
  • Stem Cell Transplantation
  • Surgical Wound (etiology, therapy)
  • Treatment Outcome
  • Wound Healing

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