Clinical Observation of Double Percutaneous Nephrostomy Combined with Ureter Occlusion Stent for Treating Cervical Cancer Complicated with Vesicovaginal Fistula.

Abstract

Background: To evaluate the efficacy of double percutaneous nephrostomy (PCN) combined with ureter occlusion stent for treating cervical cancer complicated with vesicovaginal fistula (VVF). Materials and Methods: A retrospective analysis was performed for 12 patients with cervical cancer complicated with VVF. Regardless of surgical resection, radiotherapy alone or combined chemoradiotherapy were carried out in all patients. After VVF was diagnosed by gynecological examination, imaging, and cystoscopy, concurrent double PCN and ureter occlusion stent implantation were performed for all patients. Results: All patients successfully received ureter occlusion stent implantation after nephrostomy. The success rate of nephrostomy and stent placement was 100% (12/12). After intervention, urinary fistula immediately disappeared in all patients. One week post-surgery, bilateral hydronephrosis disappeared in 4 patients, and their renal insufficiency and renal function returned to normal. One month after operation, 6 patients with genital eczema or ulcer and 5 patients with urinary tract infection were cured. During follow-up, there were no recurrence in urinary fistula, renal dysfunction, and other complications. Conclusion: Double PCN combined with ureter occlusion stent could effectively treat cervical cancer complicated with VVF hydronephrosis, urinary tract infection, and renal insufficiency and contribute to alleviate all kinds of clinical discomfort.

• Authors: Xu-Hua Duan, Feng-Yao Li, Xin-Wei Han, Gang Wu, Jian-Hao Zhang, Yu-Dong Tian, Yan-Cang Zhang
• Journal: Cancer biotherapy & radiopharmaceuticals (Cancer Biother Radiopharm) Vol. 37 Issue 9 Pg. 759-765 (Nov 2022) ISSN: 1557-8852 [Electronic] United States
• PMID: 33016777 (Publication Type: Journal Article)

Topics

• Female
• Humans
• Hydronephrosis (etiology, surgery)
• Nephrostomy, Percutaneous (adverse effects, methods)
• Renal Insufficiency (complications)
• Retrospective Studies
• Stents (adverse effects)
• Ureter (surgery)
• Urinary Fistula (complications)
• Uterine Cervical Neoplasms (complications, surgery)
• Vesicovaginal Fistula (etiology, surgery)