Hyperuricemia is prevalent throughout the world. However, a well-designed large-scale epidemiological investigation of
hyperuricemia in southwestern China is lacking. A regional representative sample of 10,141 participants were included using multistage, stratified sampling in Chengdu and Chongqing from September 2013 to March 2014.
Hyperuricemia was defined as the self-reported of the doctor's diagnosis of
hyperuricemia, or serum
uric acid > 420 μmol/L in men or serum
uric acid > 360 μmol/L in women. The overall age- and sex-standardized prevalence of
hyperuricemia among adults aged 35-79 years was 13.5%. Compared with women, the prevalence of
hyperuricemia in men was higher (17.3% versus 10.0%).
Hypertension,
hyperlipidemia,
overweight or
obesity, central obesity were associated with an increased risk for
hyperuricemia both in men and in women. Married men and women were not susceptible to
hyperuricemia. Current cigarette smoking was an associated risk factor of
hyperuricemia only in women.
Hyperuricemia has become a major health problem among urban adults aged 35-79 years in southwestern China, and special attention should be paid to men. Comorbidities associated with
hyperuricemia and causality worth further investigation.