Test-of-cure stool cultures for traveler's diarrhea.

Abstract

Whether enteropathogens were eradicated or persisted in test-of-cure stool cultures from 251 patients with traveler's diarrhea, the durations of diarrhea were similar within the antimicrobial agent-treated (32 versus 33 h) and placebo-treated (82 versus 96 h) groups. Routine test-of-cure stool cultures can be useful for evaluating treatment failures and for assessing asymptomatic carriage of enteropathogens after treatment, but they are not mandated in the design of placebo-controlled antimicrobial treatment trials in traveler's diarrhea when the focus of the trial is clinical efficacy.

• Authors: C D Ericsson, H L DuPont, J J Mathewson, P C Johnson, F J de la Cabada, J A Bitsura
• Journal: Journal of clinical microbiology (J Clin Microbiol) Vol. 26 Issue 5 Pg. 1047-9 (May 1988) ISSN: 0095-1137 [Print] United States
• PMID: 3290233 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article, Research Support, U.S. Gov't, P.H.S.)

Topics

• Carrier State (diagnosis)
• Clinical Trials as Topic
• Diarrhea (diagnosis, drug therapy)
• Feces (microbiology)
• Humans
• Travel