We report a case of full-thickness
macular hole (FTMH) which developed during follow-up for
Coats disease. To our knowledge, this is the first report on a case of FTMH which developed during follow-up for
Coats disease. A 17-year-old boy was referred to our institution with blurred vision in his left eye. Fundus examination showed yellowish subretinal exudates with overlying telangiectatic retinal vessels in the temporal periphery in the left eye; the right eye was normal.
Fluorescein angiography revealed diffusion indicative of temporal peripheral vascular leakage. We made a diagnosis of stage 2A
Coats disease and performed
argon laser photocoagulation (PC). Moreover, he received
intravitreal injection of anti-
vascular endothelial growth factor. At 30 months after the first visit, the best-corrected visual acuity (BCVA) of the left eye worsened to 20/50. We observed tensioned internal limiting membrane (ILM), serous macular detachment (SMD) and
retinal thinning; the intraretinal exudate remained. We performed PC and at 36 months after the first visit, BCVA further declined to 20/63 in his left eye and FTMH was observed. We then performed a 27-gauge pars plana
vitrectomy and ILM peeling following which the FTMH was found to have closed by 4 days after
vitrectomy. SMD gradually decreased, and BCVA improved to 20/20. Chronic
inflammation by peripheral vascular leakage and PC application might have caused FTMH. In this case, the
vitrectomy for FTMH with
Coats disease provided good visual and anatomic outcomes.