Liquid-phase exfoliation of black sesame to create a nanoplatform for in vitro photoluminescence and photothermal therapy.

Abstract

Aim: The present study aims to apply the facile liquid-phase exfoliation (LPE) strategy to fabricate 2D organic materials and thus to broaden the family of biocompatible and multifunctional 2D materials. Materials & methods: 2D material-organic melanin and cellulose nanosheets were synthesized from black sesame hull using LPE. Photoluminescence and photothermal properties of the nanosheets were assessed, as well as stability and cell killing ability. Results: The prepared 2D nanoplatform exhibited broad and multiple photoluminescent emission bands. It also demonstrated efficient photothermal cancer therapy with excellent biocompatibility. Conclusion: The present study could open an avenue in exfoliating organic materials using the LPE strategy. This could make the fabrication of multifunctional 2D organic materials more efficient and broaden the family of biocompatible 2D nanomaterials.

• Authors: Zhongjian Xie, Ruitao Lu, Yao Zhu, Minhua Peng, Taojian Fan, Peigen Ren, Bing Wang, Lin Kang, Xiaoyun Liu, Sha Li, Huixian Cui
• Journal: Nanomedicine (London, England) (Nanomedicine (Lond)) Vol. 15 Issue 21 Pg. 2041-2052 (09 2020) ISSN: 1748-6963 [Electronic] England
• PMID: 32867583 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Humans
• Nanostructures
• Phototherapy
• Photothermal Therapy
• Sesamum