Joint associations of device-measured physical activity and sleep duration with cardiometabolic health in the 1970 British Cohort Study.

Abstract

OBJECTIVES:

Multiple unhealthy lifestyle behaviors could synergistically exaggerate unfavorable health outcomes. The present study aimed to investigate the joint associations of device-measured sleep duration and physical activity with cardiometabolic health markers.

DESIGN:

A cross-sectional analysis embedded in the 46-48 years wave of the 1970 British Cohort Study.

METHODS:

4756 participants wore an activPAL3 micro accelerometer to measure physical activity and sleep duration. Outcomes included body mass index (BMI), glycated hemoglobin, triglycerides, c-reactive protein, systolic blood pressure, and total-to-high-density lipoprotein (HDL) cholesterol ratio, hypertension, and diabetes. We examined the joint associations of sleep (<7h, short; 7-9h, medium; >9h, long) and physical activity (median cut of step counts, 4740 steps/d; or moderate-to-vigorous physical activity, MVPA, 085h/d) with outcomes by generalized linear models or logistic regression.

RESULTS:

Low physical activity combined with either short or long sleep was associated with higher BMI (e.g., 2.32 [1.42, 3.23] (kg/m2) for short sleep) compared to the referent medium sleep and high physical activity combination. Low physical activity combined with long sleep was associated with a higher total-to-HDL cholesterol ratio (e.g., 0.31 [0.12, 0.49] for low step counts). Short sleep combined with low step counts showed higher odds for hypertension and diabetes (1.34 [1.06, 1.69] and 1.98 [1.07, 3.68], respectively), while short sleep combined with either low or high MVPA had higher odds for diabetes (2.04 [1.09, 3.82] and 2.07 [1.04, 4.15], respectively).

CONCLUSIONS:

Low physical activity may exaggerate the detrimental associations between inadequate sleep with BMI, blood lipids, hypertension, and diabetes.

• Authors: Bo-Huei Huang, Elif Inan-Eroglu, Mark Hamer, Emmanuel Stamatakis
• Journal: Journal of science and medicine in sport (J Sci Med Sport) Vol. 23 Issue 12 Pg. 1191-1196 (Dec 2020) ISSN: 1878-1861 [Electronic] Australia
• PMID: 32859521 (Publication Type: Journal Article)
• Copyright: Copyright © 2020 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

Chemical References

• Cholesterol, HDL
• Glycated Hemoglobin A
• Triglycerides
• hemoglobin A1c protein, human
• C-Reactive Protein

Topics

• Accelerometry (instrumentation)
• Blood Pressure
• Body Mass Index
• C-Reactive Protein (metabolism)
• Cardiometabolic Risk Factors
• Cholesterol, HDL (blood)
• Cross-Sectional Studies
• Diabetes Mellitus (epidemiology)
• Exercise (physiology)
• Female
• Glycated Hemoglobin (metabolism)
• Humans
• Hypertension (epidemiology)
• Male
• Middle Aged
• Obesity (epidemiology)
• Sleep (physiology)
• Time Factors
• Triglycerides (blood)
• United Kingdom (epidemiology)
• Wearable Electronic Devices