Perioperative Management of Children on Ketogenic Dietary Therapies.

Abstract

Ketogenic diet therapy (KDT) is an effective treatment modality for children with drug-resistant epilepsy and certain other metabolic and neurologic disorders. With a resurgence of interest in KDT, pediatric anesthesiologists are increasingly encountering children on KDT for a variety of surgical and medical procedures. Maintenance of ketosis is critical throughout the perioperative period, and if not managed appropriately, these patients are at an increased risk of seizures. This review article provides an overview of the clinical indications, contraindications, proposed anticonvulsant mechanisms, initiation, and monitoring of children on KDTs. Recommendations for the perioperative anesthetic management of children on KDT are summarized. A comprehensive table listing the carbohydrate content of common anesthetic drugs is also included.

• Authors: Zacherie R Conover, Afsaneh Talai, Katherine S Klockau, Richard J Ing, Debnath Chatterjee
• Journal: Anesthesia and analgesia (Anesth Analg) Vol. 131 Issue 6 Pg. 1872-1882 (12 2020) ISSN: 1526-7598 [Electronic] United States
• PMID: 32769381 (Publication Type: Journal Article, Review)

Chemical References

• Anesthetics
• Dietary Carbohydrates

Topics

• Anesthesia (adverse effects, methods)
• Anesthetics (administration & dosage, adverse effects)
• Child
• Diet, Ketogenic (methods)
• Dietary Carbohydrates (administration & dosage, adverse effects)
• Epilepsy (diet therapy, surgery)
• Humans
• Perioperative Care (methods)
• Treatment Outcome