High orchiectomy and ipsilateral testicular sperm extraction in a man with a testicular tumor and Klinefelter syndrome: A case report.

Abstract

INTRODUCTION:

Testicular epidermal cysts in Klinefelter syndrome are very rare. We report a case of Klinefelter syndrome associated with a testicular epidermal cyst. To our knowledge, this is the first report showing successful spermatozoa retrieval from the affected testis.

CASE PRESENTATION:

A 25-year-old married man was referred to our hospital with right scrotal induration, which was in lower pole of the right testis. Testicular cancer tumor markers were normal; endocrinological findings indicated hypergonadotropic hypogonadism. Semen analyses revealed azoospermia. Preoperative chromosome test result: 47, XXY karyotype; ultrasonography report: 1.9-cm internal heterogeneous echoic mass in the right testis (malignancy not discarded). Because the patient hoped for children, he underwent high orchiectomy with ipsilateral testicular sperm extraction (200 spermatozoa from normal testicular tissue) for future fertilization procedures. Tumor pathology was an epidermal cyst.

CONCLUSION:

While performing orchiectomy for testicular tumors, sperm retrieval should be attempted from normal tissues in patients planning for children.

• Authors: Teppei Takeshima, Mizuki Yamamoto, Daiji Takamoto, Taku Mochizuki, Shinnosuke Kuroda, Takashi Kawahara, Koji Izumi, Jun-Ichi Teranishi, Yasuhide Miyoshi, Masako Otani, Hiroji Uemura, Yasushi Yumura
• Journal: IJU case reports (IJU Case Rep) Vol. 2 Issue 2 Pg. 65-68 (Mar 2019) ISSN: 2577-171X [Electronic] Australia
• PMID: 32743375 (Publication Type: Case Reports)
• Copyright: © 2018 The Authors. IJU Case Reports published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Urological Association.