Depressive symptoms are not associated with type 2 diabetes in a rural population in China: findings from the Henan rural cohort.

Abstract

BACKGROUND:

Depression is one of the most prevalent mental health challenges that affect all groups of persons. This study examines the association between type 2 diabetes and depressive symptoms (using PHQ-2) in a rural population. Other risk factors of depressive symptoms are examined.

METHODS:

Data from 30,001 participants from the Henan rural cohort was analyzed. Multivariable logistic regression analyses were performed to examine the associations between depressive symptoms (DS) and type 2 diabetes and other risk factors. Adjusted odds ratios (aOR) with confidence intervals (CI) at 95% are reported.

RESULTS:

The prevalence of DS in the study population is 5.86%, 6.69% in women, 4.74% in men, 5.80% in persons without diabetes and 6.81% in persons with diabetes (diagnosed and undiagnosed). DS prevalence was highest in persons with previously diagnosed diabetes (8.27%). No association was found between DS and diabetes (aOR = 0.95, CI at 95% 0.61-1.48; p=0.836). DS was associated with poor glycemic control (aOR=1.43, CI at 95% 1.04- 1.98; p= 0.034) in persons with previously diagnosed diabetes, persons with elevated triglycerides (aOR=1.19, CI at 95% 1.08-1.30; p<0.001), household income (aOR= 0.78, CI at 95% 0.63-0.97; p=0.027), marital status (aOR=1.37, CI at 95% 1.01-1.88, p=0.049) and hypertension treatment with medication (aOR=1.94, CI at 95% 1.48-2.55; p<0.001).

LIMITATIONS:

DS was assessed through self-report and may suffer recall or information bias.

CONCLUSIONS:

DS was not associated with diabetes in our study population. The association between poor glycemic control and DS calls for the integration of screening for depression among patients with diabetes.

• Authors: Tanko Abdulai, Tu Runqi, Zhicheng Lou, Cecilia Amponsem-Boateng, Haiqing Zhang, Xiaotian Liu, Linlin Li, Zhenxing Mao, Wenqian Huo, Jian Hou, Fang Wang, Chongjian Wang
• Journal: Journal of affective disorders (J Affect Disord) Vol. 274 Pg. 841-847 (09 01 2020) ISSN: 1573-2517 [Electronic] Netherlands
• PMID: 32664023 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2020 Elsevier B.V. All rights reserved.

Topics

• China (epidemiology)
• Cross-Sectional Studies
• Depression (epidemiology)
• Diabetes Mellitus, Type 2 (epidemiology)
• Female
• Humans
• Male
• Prevalence
• Risk Factors
• Rural Population