How I treat anemia in the perisurgical setting.

Abstract

Anemia is a common finding in the perioperative setting with significant untoward consequences including worsening of outcomes and diminished quality of life as well as increased risk of allogeneic blood transfusions. Here, we present 3 cases that illustrate how anemia can be perioperatively managed in patients undergoing cardiac, orthopedic, and oncology surgeries. Timely detection of anemia prior to high-blood loss surgeries can allow clinicians to manage it and optimize hemoglobin level, making patients better prepared for the surgery. Treatment of anemia should be guided by the etiology and may include erythropoietic agents, folic acid, B12, and iron preparations. Other blood management strategies geared toward reducing surgical blood loss such as autologous transfusion techniques and agents to optimize hemostasis are used during surgery and in the immediate postoperative period. Patients should be closely monitored following surgery for signs of ongoing bleeding in need of control. Finally, screening for and management of anemia should continue in the postoperative and postdischarge period, as persistence and recurrence of anemia can further undermine patient's outcomes.

• Authors: Aryeh Shander, Margit Kaufman, Lawrence T Goodnough
• Journal: Blood (Blood) Vol. 136 Issue 7 Pg. 814-822 (08 13 2020) ISSN: 1528-0020 [Electronic] United States
• PMID: 32556314 (Publication Type: Journal Article, Review)
• Copyright: © 2020 by The American Society of Hematology.

Chemical References

• Erythropoietin
• Iron

Topics

• Anemia (blood, therapy)
• Blood Loss, Surgical (prevention & control)
• Blood Transfusion, Autologous (adverse effects, methods)
• Erythrocyte Transfusion (adverse effects, methods)
• Erythropoietin (administration & dosage, adverse effects)
• Humans
• Iron (administration & dosage, adverse effects)
• Perioperative Care (methods)
• Postoperative Complications (therapy)