Folic Acid (Vitamin M)

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7688 relevant articles (334 outcomes, 1119 trials/studies) found for this Drug

Description: A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (POACEAE). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia.

Also Known As:

Vitamin M; Folacin; Folate; Folic Acid, (D)-Isomer; Folic Acid, (DL)-Isomer; Folic Acid, Calcium Salt (1:1); Folic Acid, Monopotassium Salt; Folic Acid, Monosodium Salt; Folic Acid, Potassium Salt; Folic Acid, Sodium Salt; Folvite; Pteroylglutamic Acid; L-Glutamic acid, N-(4-(((2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-

Relationship Network

Drug Context: Research Results

Heterocyclic Compounds: 25

2-Ring Heterocyclic Compounds

5,11-methenyltetrahydrohomofolate: 18

Pteroylpolyglutamic Acids: 12

10-formyldihydrofolate: 2

10-formyl-7,8-dihydrofolic acid: 1

11-thiohomoaminopterin: 1

8-deazafolic acid: 1

CB 3988: 1

EC0225: 1

gamma-fluorofolic acid: 1

O(4)-benzylfolic acid: 1

tetrahydrohomofolic acid: 1

(5)N,(8)N-deaza-(10)-N-methylfolate

1',2',3',4',5',6'-hexahydrohomofolic acid

1-(4-((1-(2-amino-7-methyl-4-oxo-6-pteridinyl)ethyl)amino)phenyl)-1-deoxy-(1-ribofuranosyl)ribitol

10-acetyl-5,8-dideazafolic acid

10-formyl-5,8-dideazafolate

10-formyldihydropteroylglutamate

10-formylfolic acid

10-methyl-11-deazahomofolic acid

10-nitrofolic acid

10-propargyl-5-deazafolic acid

10-thiofolic acid

11-deazahomofolic acid

11-oxahomofolic acid

11-thiohomofolic acid

12-nitrofolic acid

2-aza-2-desamino-5,8-dideazafolic acid

2-deaminofolic acid

2-desamino-2,3-dimethyl-N(10)-propargyl-5,8-dideazafolic acid

2-desamino-2-methyl,-10-propargyl-5,8-dideaza-pteroylsulpho-glycine

2-desamino-2-methyl-10-propargyl-5,8-dideaza-pteroylsulphoglutamine

2-desamino-2-trifluoromethyl-N(10)-propargyl-5,8-dideazafolic acid

2-desamino-5,8-dideazafolic acid

3',5'-dichlorohomofolic acid

3,5-dichlorofolic acid

5,10-dideazafolic acid

5,10-methylenetetrahydro-5-deazafolic acid

5,6,7,8-tetrahydro-N(5),N(10)-carbonylfolic acid

5-deazafolic acid

5-deazaisofolic acid

5-methyl-5,6-dihydropteroylglutamic acid

5-methyldihydrofolate

5-methyltetrahydrohomofolic acid

8-deazahomofolic acid

beta,beta-difluorofolic acid

biotin-SS-folate

CB 3731

CYM protocol

deferoxamine-gamma-folate conjugate

dihydrofolate monooxygenase

dihydrohomofolic acid

folate-(BODIPY FL)-SS-rhodamine

ICI M247496

isohomofolic acid

Jectofer Compound

N(10)-bromoacetyl-5,8-dideazafolic acid

N(10)-propargylfolic acid

N(10)-tosylisohomofolic acid

N(alpha)-(5-deaza-5,6,7,8-tetrahydropteroyl)ornithine

N(alpha)-pteroyl-N(epsilon)-(4'-fluoresceinthiocarbamoyl)lysine

N-(4-((N-((2,4-diaminofuro(2,3-d)pyrimidin-5-yl)methyl)amino)methyl)benzoyl)glutamic acid

N-(4-(2-(2,4-diaminofuro(2,3-d)pyrimidin-5-yl)ethyl)benzoyl)glutamic acid

N-(4-(N-((2,4-diamino-furo(2,3-d)pyrimidin-5-yl)methyl)methylamino)benzoyl)glutamic acid

N-(4-(N-((2,4-diaminofuro(2,3-d)pyrimidin-5-yl)methyl)amino)benzoyl)glutamic acid

N-(N-(4-(N-((3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl)-2-propynylamino)benzoyl)-gamma-glutamyl)-2-aminoadipic acid

N2-(1-(carboxyethyl))folic acid

technetium 99m picolylamine monoacetic acid folate

technetium Tc 99m tricarbonyl DTPA-folate

Experts

1.	Ray, Joel G: 6 articles (05/2007 - 08/2002)
2.	Oakley, Godfrey P: 5 articles (08/2008 - 01/2002)
3.	Jaszewski, Richard: 5 articles (07/2008 - 01/2003)
4.	Jacques, Paul F: 5 articles (04/2008 - 03/2002)
5.	Rosenberg, Irwin H: 5 articles (04/2008 - 03/2002)
6.	Selhub, Jacob: 5 articles (04/2008 - 03/2002)
7.	Vermeulen, Marian J: 5 articles (05/2007 - 12/2002)
8.	Moat, Stuart J: 5 articles (05/2007 - 01/2002)
9.	Hobbs, Charlotte A: 5 articles (04/2007 - 07/2002)
10.	Cavalli-Sforza, Tommaso: 5 articles (12/2005 - 12/2005)

Related Diseases

1.	Neural Tube Defects (Exencephaly) 02/01/2009 - "Folates are important for normal neural tube closure in early gestation, and the efficacy of diet fortification with folic acid in reducing the incidence of neural tube defects is a major success story for public health nutrition. " 06/01/2008 - "A folic acid supplementation program targeting couples prior to marriage in China has led to optimal consumption of supplements containing folic acid and a significant reduction of neural tube defects (NTD). " 12/01/2008 - "These data suggest that women of childbearing age are achieving positive folate status in the postfortification era, but it may not be sufficient to achieve red blood cell folate concentrations associated with a significant reduction in neural tube defect risk. " 08/01/2008 - "BACKGROUND: Folic acid fortification of flour has significantly decreased the incidence of neural tube defects (NTDs). " 07/12/2007 - "CONCLUSIONS: Food fortification with folic acid was associated with a significant reduction in the rate of neural-tube defects in Canada. " Order ALL the reference details at left...
2.	Neoplasms (Cancer) 06/01/2003 - "Folate is one of the important constituents of vegetables and fruits that may provide protection against cancer. " 09/13/2002 - "Nevertheless, prominent examples do exist where folate targeting has significantly improved the outcome of a macromolecule-based therapy, leading to complete cures of established tumors in many cases. " 08/01/2002 - "Understanding the mechanisms by which folate status modulates carcinogenesis is important for advancing insight into cancer biology and for facilitating those efforts to translate research in folate and carcinogenesis into effective and safe public health initiatives." 11/01/1996 - "Considerably more speculative is the concept that supraphysiologic folate status may afford some protection against cancer. " 01/01/1985 - "Since FBP may decrease available intracellular folate the present data support clinical findings that chemotherapeutic agents may be more effective for ER negative tumors." Order ALL the reference details at left...
3.	Hyperhomocysteinemia 06/01/2007 - "Does lowering hyperhomocysteinemia by folic acid beneficial for oculo-Behcet's disease? " 03/01/2005 - "Folic acid supplementation also significantly decreased the incidence of damaged vessels due to hyperhomocysteinemia. " 01/01/2009 - "Our study showed that IV pharmacologic dose of Vit B12 alone is as effective as low-dose folic acid in correcting hyperhomocysteinemia in chronic HD patients, and combining both drugs in low doses may have added effects." 10/01/2004 - "These studies also attempt to address the impact, if any, of folate therapy in the reduction of cardiovascular risk, and to demonstrate if hyperhomocysteinemia is actually an independent risk factor that can be effectively treated." 01/01/2009 - "Hence, folic acid supply is useful in the treatment of hyperhomocysteinemia in HD patients, although it is not sufficient to modify their chronic inflammatory status. " Order ALL the reference details at left...
4.	Congenital Abnormalities (Deformity) 11/01/2000 - "Furthermore, it would require changes to the previous recommendations since a multivitamin containing a physiological dose of folic acid (0.5 to 0.8mg) seems to be more effective in reducing the occurrence of the first NTD and other congenital abnormalities than folic acid alone. " 01/01/2008 - "CONCLUSION: The results indicate that the risk of congenital abnormalities in children exposed in utero to CBZ, PB, PHT, and PRI is reduced but not eliminated by folic acid supplementation at 5-12 weeks from LMP. " 06/01/2004 - "Recent data show improved folate status and apparent decreases in risk of neural tube birth defects in the U.S. " 04/01/1989 - "Supplementation of the deficient serum with folic acid improved growth and greatly reduced the occurrence of deformities. " 01/01/2009 - "However, the sample size in the study was too small to determine the optimum dose or to detect whether folic acid protects against birth defects. " Order ALL the reference details at left...
5.	Anemia 08/01/1983 - "From the previous and the present studies folic acid supplements appeared to be beneficial in ameliorating the anemia. " 03/01/2004 - "Prematurity and maternal folate deficiency: anemia during pregnancy study group results in Valencia, Venezuela." 10/01/2002 - "This study was conducted to estimate the potential benefits of informing women of reproductive age who are unaware of their low folate levels, uncovered in their anemia tests. " 12/01/1990 - "Complete examination and laboratory studies revealed only a severe folate deficiency anemia. " 12/01/2008 - "Folate deficiency with anemia declined significantly in women (from 4.1% to 0.5%; OR: 0.1; 95% CI: 0.1, 0.2), but logistic regression models and standardization indicated that none of the known possible anemia causes could account for the decline in total anemia in children or women. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Vitamin B 12 (Cyanocobalamin)
2.	Folic Acid (Vitamin M)
3.	Homocysteine
4.	Vitamins
5.	Methotrexate (Mexate)
6.	Iron
7.	Vitamin B 6
8.	Micronutrients
9.	Leucovorin (Folinic Acid)
10.	Pyridoxine (Pyridoxin)

Related Therapies and Procedures

1.	Renal Dialysis (Hemodialysis)
2.	Drug Therapy (Chemotherapy)
3.	Transplantation (Transplant Recipients)
4.	Immunotherapy
5.	Oral Administration

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