Abstract | BACKGROUND: Continuous glucose monitoring (CGM) and continuous subcutaneous insulin infusion (CSII) are the standard of care for type 1 diabetes in children. There is little reported on device-related skin complications and treatment options. This study documents cutaneous reactions to CGM and CSII devices in children and young adults with type 1 diabetes. METHODS: One hundred and twenty-one subjects (3-25 years) with type 1 diabetes and CGM and/or CSII use were recruited over a three-month period from the Naomi Berrie Diabetes Center at Columbia University Irving Medical Center. A five-question survey was completed for each subject detailing demographic data, diabetes management, and device-related skin complications. RESULTS: Sixty percent of subjects reported skin complications related to CGM and/or CSII use. Terms most frequently used to describe cutaneous reactions were "red," "itchy," "painful," and " rash." Subjects who used both CGM and CSII were more likely to report skin problems than those who used only CSII (odds ratio 2.9, [95% confidence interval: 1.2-6.7]; P = .015). There were no associations between skin complications and sex or race/ethnicity. Twenty-two percent of subjects with adverse skin event(s) discontinued use of a device due to their skin problem. Seven percent were evaluated by a dermatologist. Eighty-one percent used a range of products to treat their symptoms, with variable perceived clinical outcomes. CONCLUSIONS: Skin complications related to CSII or CGM devices are commonly reported in pediatric patients with type 1 diabetes and may lead to interruption or discontinuation of device use. Future studies are needed to elucidate the causes of these reactions and determine the best methods for prevention.
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Authors | Rachel S Rigo, Laura E Levin, Donald V Belsito, Maria C Garzon, Rachelle Gandica, Kristen M Williams |
Journal | Journal of diabetes science and technology
(J Diabetes Sci Technol)
Vol. 15
Issue 4
Pg. 786-791
(07 2021)
ISSN: 1932-2968 [Electronic] United States |
PMID | 32389062
(Publication Type: Journal Article)
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Chemical References |
- Blood Glucose
- Hypoglycemic Agents
- Insulin
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Topics |
- Blood Glucose
- Blood Glucose Self-Monitoring
- Child
- Diabetes Mellitus, Type 1
(drug therapy)
- Humans
- Hypoglycemic Agents
(adverse effects)
- Insulin
(adverse effects)
- Insulin Infusion Systems
- Young Adult
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