Abstract | PURPOSE: CASE REPORT: A 41-year-old white male presented with painless, blurry vision in the left eye. Examination revealed unilateral optic nerve swelling confirmed by optical coherence tomography (OCT). Initial workup revealed mild leukocytosis, eventually diagnosed as chronic lymphocytic leukemia (CLL). No other cause of optic neuropathy was identified despite extensive investigation. The patient developed rapidly progressive retinal ganglion cell nerve fiber layer (NFL) atrophy and relative afferent pupillary defect (RAPD) of the left eye despite steroid treatment but stabilized after four cycles of CLL-targeted chemotherapy. Although infiltrative optic neuropathy is well-known in leukemia, presentation with only subtle vision loss is rare. Vision loss usually presents late in leukemic infiltrative optic neuropathy and therefore must be considered in patients with optic disc swelling and leukocytosis. CONCLUSION:
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Authors | Rajesh K Sharma, Kevin Mays |
Journal | Journal of ophthalmic & vision research
(J Ophthalmic Vis Res)
2020 Jan-Mar
Vol. 15
Issue 1
Pg. 109-112
ISSN: 2008-2010 [Print] United Arab Emirates |
PMID | 32095215
(Publication Type: Case Reports)
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Copyright | Copyright © 2020 Sharma and Mays. |