A case of acquired Brown syndrome treated with adalimumab.

Abstract

We present the case of a 4-year-old boy with acquired Brown syndrome of inflammatory origin. Without evidence of systemic inflammation, the disease typically resolves with oral steroids or nonsteroidal anti-inflammatory drugs. Refractory cases can be treated with local steroid injections or surgery. The present case of inflammatory Brown syndrome did not respond to conservative therapy, and parental concerns and wishes precluded more invasive treatments. Adalimumab was initiated and led to complete resolution of the disease.

• Authors: Kristi L Michels, Sudhi P Kurup, Megan L Curran, Risa Alperin, Erika De Leon, Rebecca Mets-Halgrimson
• Journal: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus (J AAPOS) Vol. 24 Issue 3 Pg. 167-169 (06 2020) ISSN: 1528-3933 [Electronic] United States
• PMID: 32087325 (Publication Type: Case Reports)
• Copyright: Copyright © 2020 American Association for Pediatric Ophthalmology and Strabismus. Published by Elsevier Inc. All rights reserved.

Chemical References

• Anti-Inflammatory Agents
• Steroids
• Adalimumab

Topics

• Adalimumab (therapeutic use)
• Anti-Inflammatory Agents
• Child, Preschool
• Humans
• Male
• Ocular Motility Disorders (drug therapy)
• Steroids