Metal-Organic Frameworks for Photodynamic Therapy: Emerging Synergistic Cancer Therapy.

Abstract

Photodynamic therapy (PDT) conducted by photosensitizers producing cytotoxic reactive oxygen species (ROS) under light irradiation is widely used in cancer treatment. A great number of photoactive nanoscale metal-organic frameworks (NMOFs) have been prepared for PDT. With the development of biomedicine and nanotechnology, many synergistic cancer therapies have emerged. In this mini-review, an overview on the latest progress in the application of NMOFs in PDT is provided, with emphasis on the recent emergence of some synergistic therapies.

• Authors: Yucong Song, Lei Wang, Zhigang Xie
• Journal: Biotechnology journal (Biotechnol J) Vol. 16 Issue 2 Pg. e1900382 (Feb 2021) ISSN: 1860-7314 [Electronic] Germany
• PMID: 32022449 (Publication Type: Journal Article, Review)
• Copyright: © 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Chemical References

• Antineoplastic Agents
• Metal-Organic Frameworks
• Photosensitizing Agents
• Reactive Oxygen Species

Topics

• Antineoplastic Agents (therapeutic use)
• Metal-Organic Frameworks (therapeutic use)
• Neoplasms (drug therapy)
• Photochemotherapy
• Photosensitizing Agents (therapeutic use)
• Reactive Oxygen Species