Abstract |
The nucleotide sequences of the hemagglutinin genes of four norakin-resistant mutants of Influenza A/FPV/Weybridge were determined and compared to the wild-type hemagglutinin. All mutants show one or two amino acid substitutions which are discussed to destabilise the pH 7 conformation of hemagglutinin.
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Authors | S Prösch, H Heider, C Schroeder, D H Krüger |
Journal | Archives of virology
(Arch Virol)
Vol. 102
Issue 1-2
Pg. 125-9
( 1988)
ISSN: 0304-8608 [Print] Austria |
PMID | 3196166
(Publication Type: Journal Article)
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Chemical References |
- Hemagglutinins, Viral
- Piperidines
- triperiden
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Topics |
- Amino Acid Sequence
- Drug Resistance, Microbial
- Genes, Viral
- Hemagglutinins, Viral
(genetics)
- Influenza A virus
(drug effects, genetics)
- Piperidines
(pharmacology)
- Structure-Activity Relationship
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