Physiological growth hormone (GH) secretion during the recovery from psychosocial dwarfism: a case report.

Abstract

We describe a 6.4 year old boy who had reversible GH insufficiency secondary to psychosocial dwarfism. On removal to a more favourable environment we observed the recovery of physiological GH secretion by progressive increase in GH pulse amplitude. These observations are relevant to our understanding of the control of GH secretion in that GH pulse frequency appears invariable and alteration in GH secretion is by pulse amplitude modulation.

• Authors: R Stanhope, P Adlard, G Hamill, J Jones, D Skuse, M A Preece
• Journal: Clinical endocrinology (Clin Endocrinol (Oxf)) Vol. 28 Issue 4 Pg. 335-9 (Apr 1988) ISSN: 0300-0664 [Print] England
• PMID: 3191602 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Growth Hormone

Topics

• Child
• Dwarfism (etiology, physiopathology)
• Growth Hormone (metabolism)
• Humans
• Male
• Psychosocial Deprivation
• Secretory Rate
• Sleep Stages (physiology)
• Time Factors