Inflammatory pseudotumor-like follicular dendritic cell sarcoma: A brief report of two cases.

Abstract

BACKGROUND:

Follicular dendritic cell (FDC) sarcoma/tumor is a rare malignant tumor of follicular dendritic cells, which is considered a low-grade sarcoma that can involve lymph nodes or extranodal sites. Conventional FDC sarcomas are negative for Epstein-Barr virus (EBV), whereas the inflammatory pseudotumor-like variant consistently shows EBV in the neoplastic cells.

CASE SUMMARY:

We report two cases of inflammatory pseudotumor-like FDC sarcoma in the liver that received 3D laparoscopic right hepatectomy and open right hepatectomy separately.

CONCLUSION:

EBV probe-based in situ hybridization and detection of immunohistochemical markers of FDC play an important role in the diagnosis and differential diagnosis of inflammatory pseudotumor-like FDC sarcoma. Complete surgical excision combined with regional lymphadenectomy may be effective in reducing the postoperative recurrence and metastasis and improving long-term survival rates.

• Authors: Bi-Xi Zhang, Zhi-Hong Chen, Yu Liu, Yuan-Jun Zeng, Yan-Chun Li
• Journal: World journal of gastrointestinal oncology (World J Gastrointest Oncol) Vol. 11 Issue 12 Pg. 1231-1239 (Dec 15 2019) ISSN: 1948-5204 [Print] China
• PMID: 31908727 (Publication Type: Case Reports)
• Copyright: ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.