A Case of Recurrent Peritoneal Cancer in Which an Antitumor Effect Was Obtained Using a Combination of Etoposide and a Chinese Herbal Medicine with Maintenance of Daily Life.
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| Abstract |
The patient was a 50-year-old multiparous female (gravida/para 4/2) who had divorced. She was followed up for 1 year and 5 months after completion of initial treatment for peritoneal cancer (preoperative chemotherapy + optimal surgery + chemotherapy). A gradual increase in the tumor marker CA125 occurred, and computed tomography and ultrasonography showed bilateral neck, left supraclavicular and right axillary lymphadenopathy. The patient wanted to continue her job. Therefore, she was treated with etoposide (25 mg) daily for 3 weeks and TJ-48 (juzen-taihoto, 7.5 g) daily for 4 weeks, and then followed up. After two weeks, swelling of lymph nodes had been reduced or eliminated and tumor marker CA125 was negative. The only adverse reaction was slight numbness and the patient continued to work while receiving the same drugs orally for 2 years and 8 months without any symptoms or recurrence. This case shows that a combination of etoposide and TJ-48 has an antitumor effect on recurrent progressive peritoneal cancer while allowing a patient to work and have a normal daily life.
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| Authors | Toshinari Muramatsu, Tetsuji Iida, Yuki Kuriyama, Takatoshi Manabe, Ippei Oiwa, Rie Nakajima, Chisa Narayama, Tomoaki Narayama, Noriko Miyatake, Kenichi Goya, Hironobu Maeda, Mikio Mikami |
| Journal | The Tokai journal of experimental and clinical medicine (Tokai J Exp Clin Med) Vol. 44 Issue 4 Pg. 90-93 (Dec 20 2019) ISSN: 2185-2243 [Electronic] Japan |
| PMID | 31768997 (Publication Type: Case Reports, Journal Article) |
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