Abstract | BACKGROUND:
Thymoquinone is a promising anticancer molecule, the chemopreventive role of which is well-known at least in vitro and in the animal model. In this review article, we focused on the anti-inflammatory activities of thymoquinone in cancer cells. METHOD: Research data on inflammation, cancer and thymoquinone were acquired from PubMed, Scopus, Web of Science and Google Scholar. We reviewed papers published since the mid of the last century, and the most cited papers of the last ten years. RESULTS: CONCLUSION: This article reviewed the role of inflammation on cancer development, and the action of thymoquinone on inflammatory molecules, which have been proved in vitro and in vivo. Much attention is required for studying the role of thymoquinone in immunotherapeutics and developing this molecule as a future anticancer drug.
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Authors | Zakia Akter, Faiza Rafa Ahmed, Mousumi Tania, Md Asaduzzaman Khan |
Journal | Current medicinal chemistry
(Curr Med Chem)
Vol. 28
Issue 1
Pg. 80-92
( 2021)
ISSN: 1875-533X [Electronic] United Arab Emirates |
PMID | 31604405
(Publication Type: Journal Article, Review)
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Copyright | Copyright© Bentham Science Publishers; For any queries, please email at [email protected]. |
Chemical References |
- Anti-Inflammatory Agents
- Antineoplastic Agents
- Benzoquinones
- Inflammation Mediators
- Intercellular Signaling Peptides and Proteins
- Interleukins
- NF-kappa B
- Tumor Necrosis Factor-alpha
- thymoquinone
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Topics |
- Animals
- Anti-Inflammatory Agents
(pharmacology)
- Antineoplastic Agents
(pharmacology)
- Benzoquinones
(pharmacology)
- Humans
- Immunotherapy
- Inflammation Mediators
(antagonists & inhibitors)
- Intercellular Signaling Peptides and Proteins
- Interleukins
- NF-kappa B
- Neoplasms
(drug therapy)
- Tumor Necrosis Factor-alpha
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