In 1976 Goldman M. and Kronman J. reported on the effects of a N-monochloro-DL-2 aminobutyrate (NMAB)
solution used as a caries removal agent. Since that time various studies demonstrated the safety and clinical acceptability of the
solution. No adverse side effects have been reported for NMAB. NMAB is formed in aqueous
solution through the reaction of two separate components supplied as
Caridex solution I (dilute DL-2-aminobutyric acid) and II (
sodium hypochloride in weak alkaline
solution). The
Caridex delivery system includes a pump, a heater, a
solution reservoir and a handpiece to hold the applicator tip. The
Caridex is based on the softening effect of NMAB, when it is applied continuously with the applicator tip to
carious lesions. In addition to the
Caridex rotary instruments and other devices ordinarily used for cavity preparation are used as required
Caridex reduce patient
pain and anxiety but also has limitations. It cannot totally replace the conventional methods of caries removal and cavity preparation. It can be used on a supplementary method for caries removal, also it is necessary to balance a some what longer treatment time against its advantages.