The plant hormone kinetin in disease therapy and healthy aging.

Abstract

It has been more than 60 years since the discovery of kinetin, the first known member of a group of plant hormones called cytokinins. In this review we summarize the health-promoting activity of kinetin in animal systems, ranging from cells cultured in vitro through invertebrates to mammals. Kinetin has been shown to modulate aging, to delay age-related physiological decline and to protect against some neurodegenerative diseases. We also review studies on its mechanism of action, as well as point out gaps in our current knowledge.

• Authors: Alena Kadlecová, Barbara Maková, Marta Artal-Sanz, Miroslav Strnad, Jiří Voller
• Journal: Ageing research reviews (Ageing Res Rev) Vol. 55 Pg. 100958 (11 2019) ISSN: 1872-9649 [Electronic] England
• PMID: 31479763 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
• Copyright: Copyright © 2019 Elsevier B.V. All rights reserved.

Chemical References

• Cytokinins
• Kinetin

Topics

• Aging
• Animals
• Cytokinins
• Healthy Aging
• Humans
• Kinetin (pharmacology, therapeutic use)