Abstract | OBJECTIVE: PATIENTS AND METHODS: In a clinical case series, 544 women with PCOS were included in this study. Body mass index (BMI), Homeostasis Model Assessment (HOMA), Quantitative Insulin Sensitivity Check Index (QUICKI), and Matsuda index were calculated. Sixty-three women with PCOS and 50 age- and BMI-matched control patients underwent blood sampling for AMH level. RESULTS: The most common clinical presentation of PCOS in this study was menstrual irregularity followed by hirsutism and infertility. There was no statistically significant difference in the clinical presentation or hormonal profile in women with PCOS according to different BMI categories. The prevalence of insulin resistance among women with PCOS was 37.7%, 69.3%, and 75.8% using HOMA, QUICKI, and Matsuda index, respectively. Furthermore, the Matsuda index had the highest detection rate of insulin resistance, especially in underweight women with PCOS (94.1%). AMH levels in women with PCOS were significantly higher than that in the control group (P-value = 0.015). CONCLUSION:
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Authors | Lama Shahin, Dana Hyassat, Anwar Batieha, Yousef Khader, Mohammed El-Khateeb, Kamel Ajlouni |
Journal | Current diabetes reviews
(Curr Diabetes Rev)
Vol. 16
Issue 5
Pg. 483-489
( 2020)
ISSN: 1875-6417 [Electronic] United Arab Emirates |
PMID | 31441729
(Publication Type: Journal Article)
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Copyright | Copyright© Bentham Science Publishers; For any queries, please email at [email protected]. |
Chemical References |
- Insulin
- Anti-Mullerian Hormone
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Topics |
- Anti-Mullerian Hormone
(blood)
- Body Mass Index
- Female
- Humans
- Insulin
(blood, metabolism)
- Insulin Resistance
- Obesity
(blood, physiopathology)
- Polycystic Ovary Syndrome
(blood, physiopathology)
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