Abstract |
Background: We aimed to reduce the morbidity related to treatment and to preserve organ function in patients with hypopharyngeal squamous cell carcinoma (HPSCC) by applying a new surgical treatment protocol based on transoral robotic surgery (TORS). Aims/objectives: In this study, we analyzed the prognostic factors related to survival to confirm the validity and effectiveness of TORS in patients with advanced-stage HPSCC. Methods: We retrospectively analyzed the data of 44 HPSCC patients who had undergone TORS-based therapy. Results: In univariate analysis, only the surgical marginal status showed a statistically significant correlation with the survival of the patients (p = .009). In multivariate analysis, surgical margin status was the only statistically significant prognostic factor related to survival (p = .008). Forty-one patients (93.2%) recovered speech function sufficiently to perform daily conversation without artificial aids. Forty-one patients (93.2%) were able to ingest food orally. Conclusions: In the treatment of advanced hypopharyngeal cancer, TORS-based therapy helped the surgeon obtain a clear surgical margin in patients with HPSCC, and it showed superior oncologic and functional outcomes compared to the existing treatment methods.
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Authors | Young Min Park, Da Hee Kim, Min Seok Kang, Jae Yol Lim, Yoon Woo Koh, Se-Heon Kim |
Journal | Acta oto-laryngologica
(Acta Otolaryngol)
Vol. 139
Issue 9
Pg. 816-822
(Sep 2019)
ISSN: 1651-2251 [Electronic] England |
PMID | 31268399
(Publication Type: Journal Article)
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Topics |
- Adult
- Aged
- Analysis of Variance
- Cohort Studies
- Disease-Free Survival
- Female
- Humans
- Hypopharyngeal Neoplasms
(drug therapy, mortality, pathology, surgery)
- Male
- Margins of Excision
- Middle Aged
- Minimally Invasive Surgical Procedures
(methods, mortality)
- Mouth
- Natural Orifice Endoscopic Surgery
(methods)
- Neoadjuvant Therapy
- Neoplasm Invasiveness
(pathology)
- Neoplasm Staging
- Predictive Value of Tests
- Prognosis
- Retrospective Studies
- Risk Assessment
- Robotic Surgical Procedures
(methods)
- Squamous Cell Carcinoma of Head and Neck
(drug therapy, mortality, pathology, surgery)
- Survival Analysis
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