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Arachidonic acid and male genital differentiation.

Abstract
Arachidonic acid (AA) prevents neural tube/defects, cleft palate, and micrognathia in the rat models of diabetic embryopathy and neural tube defects in the mouse embryo culture model. In this study, the involvement of AA in the male genital differentiation was described. These observations raise the complementary possibility that the AA-prostaglandin biochemical pathway may be a major mechanism mediating many embryonic events that involve cellular movement and fusion.
AuthorsA S Goldman
JournalEuropean journal of pediatrics (Eur J Pediatr) Vol. 146 Suppl 2 Pg. S63-6 ( 1987) ISSN: 0340-6199 [Print] Germany
PMID3121337 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Arachidonic Acids
  • Prostaglandins
  • Arachidonic Acid
Topics
  • Animals
  • Arachidonic Acid
  • Arachidonic Acids (physiology)
  • Genitalia, Male (embryology)
  • Humans
  • Male
  • Mice
  • Neural Tube Defects (prevention & control)
  • Prostaglandins (physiology)
  • Rats
  • Sex Differentiation

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