Arachidonic Acid (Vitamin F)

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4117 relevant articles (96 outcomes, 357 trials/studies) found for this Bio-Agent

Description: An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.

Also Known As:

Vitamin F; (all-Z)-5,8,11,14-Eicosatetraenoic acid; Arachidonic Acid, (all-Z)-Isomer, 1-(14)C-Labeled; Arachidonic Acid, (all-Z)-isomer, 3H-Labeled; Arachidonic Acid, Ammonium Salt, (all-Z)-Isomer; Arachidonic Acid, Cerium Salt, (all-Z)-Isomer; Arachidonic Acid, Cesium Salt, (all-Z)-Isomer; Arachidonic Acid, Lithium Salt, (all-Z)-Isomer; Arachidonic Acid, Potassium Salt, (all-Z)-Isomer; Arachidonic Acid, Sodium Salt; Arachidonic Acid, Sodium Salt, (all-Z)-Isomer; Arachidonic Acid, Zinc Salt, (all-Z)-Isomer; Sodium Arachidonate; Arachidonate, Sodium; 5,8,11,14-Eicosatetraenoic acid, (all-Z)-

Relationship Network

Bio-Agent Context: Research Results

Lipids: 13939

Fatty Acids: 4922

Unsaturated Fatty Acids: 2398

Eicosanoids: 1178

Arachidonic Acids: 78

Arachidonic Acid: 4117

FOG7 chemotactic

Essential Fatty Acids: 472

Arachidonic Acids: 78

Arachidonic Acid: 4117

FOG7 chemotactic

Arachidonic Acids: 78

Arachidonic Acid: 4117

FOG7 chemotactic

Experts

1.	Rapoport, Stanley I: 6 articles (09/2008 - 07/2002)
2.	Bazinet, Richard P: 4 articles (10/2007 - 01/2006)
3.	Chang, Lisa: 3 articles (10/2007 - 03/2006)
4.	Falck, J R: 3 articles (09/2007 - 12/2000)
5.	Bianchi, Arnaud: 3 articles (09/2004 - 06/2002)
6.	Bécuwe, Philippe: 3 articles (09/2004 - 06/2002)
7.	Dauça, Michel: 3 articles (09/2004 - 06/2002)
8.	Martinasso, Germana: 2 articles (10/2008 - 06/2006)
9.	Lee, S H: 2 articles (04/2008 - 03/2000)
10.	Munaron, Luca: 2 articles (04/2008 - 01/2005)

Related Diseases

1.	Inflammation 01/01/2003 - "CONCLUSION: A diet low in arachidonic acid ameliorates clinical signs of inflammation in patients with RA and augments the beneficial effect of fish oil supplementation." 01/01/1991 - "However, the drug was less effective in reducing conjunctival inflammation induced by 1% sodium arachidonate. " 09/01/2006 - "Because the clinical behavior of PAF parallels that of inflammation following surgery, we investigated the effect of the inflammatory mediator arachidonic acid on the electrical behavior of normal atrial tissue in vitro and assessed the efficacy of the topical application of anti-inflammatory drugs at suppressing PAF in an animal model. " 01/01/1995 - "Reduced production of arachidonic acid metabolites may also contribute to improvement in the bronchial inflammation." 11/01/2003 - "In the present study, we investigated the individual roles of arachidonic acid metabolism in H2O2 generation in mouse skin inflammation. " Order ALL the reference details at left...
2.	Edema 04/01/1999 - "All these compounds proved to be effective against 12-O-tetradecanoylphorbol-13-acetate-induced ear edema in mice, although lacking activity against arachidonic acid-induced edema. " 01/01/1993 - "The arachidonic acid (AA)-induced ear edema model in the mouse has been demonstrated as an effective in vivo experimental tool to screen compounds showing anti-inflammatory activity. " 06/06/2002 - "In addition, the N-substituted tetrahydrophthalazinones under study were investigated for their in vivo antiinflammatory activities by examining the suppression of arachidonic acid (AA) induced mouse ear edema formation. " 09/01/2008 - "It also showed in vivo anti-inflammatory activity against arachidonic acid-induced mouse ear edema. " 09/01/2007 - "In an arachidonic acid-induced mouse ear swelling model, the extract decreased edema in a dose-dependent manner. " Order ALL the reference details at left...
3.	Bipolar Disorder (Mania) 05/01/2008 - "Chronic administration to rats of mood-stabilizers that are effective against mania in bipolar disorder, is reported to downregulate markers of the brain arachidonic acid cascade. " 09/01/2007 - "These results are consistent with the hypothesis that drugs effective in treating the manic phase of bipolar disorder decrease brain arachidonic acid turnover." 11/01/2006 - "Assuming that stages of bipolar disorder are related to brain arachidonic acid metabolism, we hypothesized that drugs effective in depression would increase cPLA(2) activity. " 10/01/2009 - "Future basic and clinical studies on the arachidonic acid hypothesis of bipolar disorder are warranted." 10/01/2009 - "Is the brain arachidonic acid cascade a common target of drugs used to manage bipolar disorder?" Order ALL the reference details at left...
4.	Neoplasms (Cancer) 04/01/1996 - "Previous studies demonstrated a requirement for arachidonic acid metabolites in tumor development in mouse skin. " 03/01/1994 - "In this study, we analyzed the biosynthesis of mono HETEs from arachidonic acid in tumor cells of different metastatic ability and correlated biosynthesis to metastatic potential. " 01/01/1992 - "The studies described herein were undertaken with the objective of determining the effect of modulation of arachidonic acid metabolism on proliferation of rat mammary tumor cells in culture. " 01/01/1990 - "This suggests that the study of arachidonic acid metabolism may contribute to characterization of the primary cancer and lead to better understanding of the mechanisms of tumor growth and diffusion." 08/15/2009 - "Arachidonic acid levels were 10 times higher in mammary tumor tissue than in the normal mammary gland across all groups and were positively correlated with tumor weight. " Order ALL the reference details at left...
5.	Asthma (Bronchial Asthma) 12/01/1999 - "To assess whether the clinical efficacy of TXA2 antagonist is predictable on the basis of urinary arachidonic acid metabolites in urine of patients with asthma, an open and multicentre trial was conducted. " 01/01/1984 - "[Experimental study on the significance of arachidonic acid metabolism in the pathogenesis of bronchial asthma with an in vivo model in the guinea pig]" 03/01/2006 - "n-6 PUFA: there was a strong positive association between arachidonic acid levels and current asthma (OR(4th quartile) 4.54, 1.77-11.62) and a negative association with FEV(1) (P=0.036). " 01/01/2000 - "Arachidonic acid metabolism in inflammatory cells of patients with bronchial asthma." 12/01/1998 - "Inhibitors of arachidonic acid metabolism have been used in asthma treatment. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)
2.	Aspirin (Acetylsalicylic Acid)
3.	Phospholipids
4.	Lithium
5.	Carbamazepine (Tegretol)
6.	Prostaglandins
7.	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)
8.	Indomethacin (Indometacin)
9.	Collagen
10.	Epoprostenol (Prostacyclin)

Related Therapies and Procedures

1.	Oral Administration
2.	Ligation
3.	Microspheres (Microsphere)
4.	Vegetarian Diet (Vegetarianism)
5.	Tonsillectomy

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