A case of bilateral Parry-Romberg syndrome successfully treated with hyaluronic acid filler augmentation.

Abstract

Parry-Romberg syndrome is a rare acquired neurocutaneous disorder typically characterized by hemifacial atrophy. Few cases of bilateral facial involvement have been reported. We report a case of a 60-year-old female with a 20-year history of progressive bilateral facial atrophy. Although an initial diagnosis of acquired partial lipodystrophy was considered, a diagnosis of bilateral Parry-Romberg was favored for three main reasons: (a) lipoatrophy was confined to the face (b) imaging findings of enophthalmos and underlying white matter changes (c) laboratories showing absence of C3 nephritic factor and normal complement levels. The patient was treated with hyaluronic acid fillers with dramatic improvement in cosmetic appearance.

• Authors: Jacqueline Watchmaker, Dana Saadeh, Christina Lam, Neelam A Vashi
• Journal: Journal of cosmetic dermatology (J Cosmet Dermatol) Vol. 18 Issue 5 Pg. 1261-1263 (Oct 2019) ISSN: 1473-2165 [Electronic] England
• PMID: 30985058 (Publication Type: Journal Article)
• Copyright: © 2019 Wiley Periodicals, Inc.