Effect of broth from meat of linseed-fed cattle on glucose-stimulated insulin release in healthy male volunteers.

Abstract

Polyunsaturated fatty acid consumption has been shown to improve insulin sensitivity. We studied if administration of broth with beef meat enriched with polyunsaturated fatty acids influenced glucose-stimulated insulin release in healthy male volunteers. Broth was made either from cattles undergone dietary supplementation with lightly bruised whole linseed in addition to feeding ad libitum on grass silage (test meal) or from those fed grass silage alone (control meal). Oral glucose tolerance tests (OGTT) were performed in patients after a 6-day period of eating 300 ml broth containing 100 g meat once a day in addition to their otherwise normal mixed nourishment. During OGTT, blood samples were taken for blood glucose level and plasma insulin immunoreactivity before and 15, 30, 60, 90, 120, and 180 min after the glucose load. Glucose-stimulated maximum increase in plasma insulin immunoreactivity was 42 ± 6.6 and 81 ± 7.4 mU/ml (p < 0.05) after the test and the control meals, respectively. However, both fasting and postload blood glucose levels were the same after either meal period. The results suggest an insulin-sensitizing effect of food produced from beef cattle maintained on linseed diet in healthy human volunteers.

• Authors: Zoltan Bacs, Katalin Szabo, Levente Czegledi, Jozsef Nemeth, Peter Fraknoi, Peter Kovacs, Andras Javor, Balazs Varga, Bela Juhasz, Zoltan Szilvassy
• Journal: Animal science journal = Nihon chikusan Gakkaiho (Anim Sci J) Vol. 90 Issue 6 Pg. 769-773 (Jun 2019) ISSN: 1740-0929 [Electronic] Australia
• PMID: 30977236 (Publication Type: Journal Article)
• Copyright: © 2019 The Authors. Animal Science Journal published by John Wiley & Sons Australia, Ltd on behalf of Japanese Society of Animal Science.

Chemical References

• Blood Glucose
• Fatty Acids, Unsaturated
• Glucose

Topics

• Adult
• Blood Glucose (metabolism)
• Fatty Acids, Unsaturated (isolation & purification, pharmacology)
• Flax
• Glucose (pharmacology)
• Glucose Tolerance Test
• Humans
• Insulin Secretion (drug effects)
• Male
• Meat (analysis)
• Silage
• Young Adult