Abstract |
Four new C-geranyl flavonoids, paulownione D-G (1-4) were isolated from the 50% acetone-H2O extract of the flowers of Paulownia fortunei. The structures of the compounds were determined by extensive spectroscopic analyses (UV, IR, HR-ESI-MS, 1D and 2D NMR). All of the compounds (1-4) exhibited potent protection effects in H9c2 cardiocytes against the lipopolysaccharide (LPS)-induced inflammation.
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Authors | Jing-Ke Zhang, Meng Li, Miao Li, Kun Du, Jinjin Lv, Zhi-Guang Zhang, Xiao-Ke Zheng, Wei-Sheng Feng |
Journal | Natural product research
(Nat Prod Res)
Vol. 34
Issue 22
Pg. 3189-3198
(Nov 2020)
ISSN: 1478-6427 [Electronic] England |
PMID | 30698037
(Publication Type: Journal Article)
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Chemical References |
- Anti-Inflammatory Agents, Non-Steroidal
- Flavonoids
- Lipopolysaccharides
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Topics |
- Animals
- Anti-Inflammatory Agents, Non-Steroidal
(chemistry, pharmacology)
- Cell Line
- Drug Evaluation, Preclinical
- Flavonoids
(chemistry, pharmacology)
- Flowers
(chemistry)
- Inflammation
(chemically induced, drug therapy)
- Lamiales
(chemistry)
- Lipopolysaccharides
(toxicity)
- Magnetic Resonance Spectroscopy
- Molecular Structure
- Myocytes, Cardiac
(drug effects)
- Rats
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