Impulse control disorders in Parkinson's disease: A systematic review on risk factors and pathophysiology.

Abstract

AIM:

Purpose of this review is to evaluate the potential risk factors that may predispose to the development of Impulse control disorders (ICDs) in Parkinson's Disease (PD) patients, including the effects of dopaminergic therapy.

METHODS:

This descriptive review was conducted to identificate risk factors that could cause impulsive control disorders in PD. Studies were found on PubMed (2010-2018), Web Of Science (January 2010-July 2018) and Cochrane (2010-2018) databases.

RESULTS:

The data suggest that intrinsic and extrinsic factors may be involved in the development of behavioral complications. To date, the link between PD and the development of ICDs is not very clear, but studies highlight the existence of a predisposition to ICDs in the presence of risk factors.

CONCLUSIONS:

A better assessment of the behavioral disorders of PD may be useful in the rehabilitative intervention for increasing the quality of life.

• Authors: Desiree Latella, Maria Grazia Maggio, Giuseppa Maresca, Anna Federica Saporoso, Maria Le Cause, Alfredo Manuli, Demetrio Milardi, Placido Bramanti, Rosaria De Luca, Rocco Salvatore Calabrò
• Journal: Journal of the neurological sciences (J Neurol Sci) Vol. 398 Pg. 101-106 (Mar 15 2019) ISSN: 1878-5883 [Electronic] Netherlands
• PMID: 30690412 (Publication Type: Journal Article, Systematic Review)
• Copyright: Copyright © 2019 Elsevier B.V. All rights reserved.

Chemical References

• Dopamine Agents

Topics

• Brain (drug effects, physiopathology)
• Disruptive, Impulse Control, and Conduct Disorders (chemically induced, epidemiology, physiopathology)
• Dopamine Agents (adverse effects, therapeutic use)
• Humans
• Parkinson Disease (drug therapy, epidemiology, physiopathology)
• Risk Factors