Abstract | BACKGROUND: A few cases of spontaneous regression of germ cell tumors have been reported. Possible mechanisms include steroid medication, surgical intervention, diagnostic radiation exposure, and immune response. None of these hypotheses has been supported by sufficient data. CASE DESCRIPTION: CONCLUSIONS: This unusual phenomenon of spontaneous regression of germinoma may be caused by a combination of pathognomonic characteristics of anatomic location with paraventricular development and stress induction as a trigger, such as salvage surgery or diagnostic radiation, including at extremely low dosage.
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Authors | Kazuma Doi, Terushige Toyooka, Kojiro Wada, Naoki Otani, Satoru Takeuchi, Arata Tomiyama, Hirokazu Nakatogawa, Tokutaro Tanaka, Hideyuki Shimazaki, Katsumi Hayashi, Kentaro Mori |
Journal | World neurosurgery
(World Neurosurg)
Vol. 124
Pg. 178-183
(Apr 2019)
ISSN: 1878-8769 [Electronic] United States |
PMID | 30659974
(Publication Type: Journal Article)
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Copyright | Copyright © 2019 Elsevier Inc. All rights reserved. |