Abstract | OBJECTIVE: Infertile women requiring ovarian stimulation and assisted reproduction techniques (ART) are faced with difficult issues. The fear that using hormones could increase their risk of cancer is the most significant. One of the main challenges for assessing cancer risk after ART is the difficulty to separate it from the underlying condition of infertility per se. The delay or the inability to achieve a pregnancy is an important risk factor for breast, endometrial and ovarian cancer. We analyzed the current literature on the topic. MATERIALS AND METHODS: RESULTS: CONCLUSIONS: Women can be reassured that fertility drugs do not appear to significantly increase the risk of invasive ovarian, endometrial, breast or other cancers, while achieving a pregnancy at an earlier age is a significant protective factor.
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Authors | L Del Pup, F A Peccatori, P E Levi-Setti, G Codacci-Pisanelli, P Patrizio |
Journal | European review for medical and pharmacological sciences
(Eur Rev Med Pharmacol Sci)
Vol. 22
Issue 22
Pg. 8042-8059
(11 2018)
ISSN: 2284-0729 [Electronic] Italy |
PMID | 30536354
(Publication Type: Journal Article, Review)
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Chemical References |
- Fertility Agents, Female
- Clomiphene
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Topics |
- Adult
- Clomiphene
(administration & dosage, adverse effects)
- Counselors
(standards)
- Female
- Fertility Agents, Female
(administration & dosage, adverse effects)
- Fertilization in Vitro
(adverse effects, methods)
- Humans
- Infertility, Female
(epidemiology, therapy)
- Neoplasms
(chemically induced, epidemiology)
- Ovulation Induction
(adverse effects, methods)
- Pregnancy
- Reproductive Techniques, Assisted
(adverse effects)
- Risk Factors
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