Abstract | BACKGROUND: Adjuvant therapy after breast surgery, including tamoxifen or aromatase inhibitors, improves the postoperative outcomes and long-term survival of breast cancer patients. The aim of this study was to determine whether volume changes occurred in the contralateral breast during hormonal or other adjuvant therapies. METHODS: This study reviewed 90 patients who underwent unilateral breast reconstruction between September 2012 and April 2018 using tissue expanders and a permanent implant after the surgical removal of breast cancer. The volume of the contralateral breast was measured using a cast before the first ( tissue expander insertion) and second (permanent implant change) stages of surgery. Changes in breast volume were evaluated to determine whether adjuvant therapy such as hormonal therapy, chemotherapy, and radiation therapy influenced the volume of the contralateral breast. RESULTS: CONCLUSIONS: Patients who received tamoxifen therapy showed a significant decrease in volume in the contralateral breast, while no significant change in weight or body mass index was found. Our findings suggest that we should choose smaller implants for premenopausal patients, who have a high likelihood of receiving tamoxifen therapy.
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Authors | Jung Youl Park, Jae-Ho Chung, Hyung Chul Lee, Byung-Il Lee, Seung-Ha Park, Eul-Sik Yoon |
Journal | Archives of plastic surgery
(Arch Plast Surg)
Vol. 45
Issue 5
Pg. 432-440
(Sep 2018)
ISSN: 2234-6163 [Print] Korea (South) |
PMID | 30282414
(Publication Type: Journal Article)
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