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Tamoxifen

One of the SELECTIVE ESTROGEN RECEPTOR MODULATORS with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the ENDOMETRIUM.
Also Known As:
ICI-46,474; ICI-46474; ICI-47699; Nolvadex; Novaldex; Soltamox; Tamoxifen Citrate; Tomaxithen; Zitazonium; Citrate, Tamoxifen; ICI 46,474; ICI 46474; ICI 47699; ICI46,474; ICI46474; ICI47699; Ethanamine, 2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-, (Z)-
Networked: 14288 relevant articles (1430 outcomes, 3515 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Jordan, V Craig: 84 articles (05/2022 - 01/2002)
2. Cuzick, Jack: 73 articles (01/2022 - 01/2003)
3. Ingle, James N: 65 articles (01/2021 - 01/2002)
4. Stål, Olle: 61 articles (05/2022 - 01/2003)
5. Dowsett, Mitch: 57 articles (01/2022 - 01/2002)
6. Howell, Anthony: 52 articles (07/2021 - 04/2002)
7. Costantino, Joseph P: 50 articles (02/2018 - 06/2002)
8. Wolmark, Norman: 48 articles (01/2019 - 06/2002)
9. Nordenskjöld, Bo: 47 articles (05/2022 - 01/2003)
10. Gelber, Richard D: 45 articles (02/2021 - 09/2003)

Related Diseases

1. Breast Neoplasms (Breast Cancer)
2. Neoplasms (Cancer)
3. Neoplasm Metastasis (Metastasis)
4. Endometrial Neoplasms (Endometrial Cancer)
5. Gynecomastia

Related Drugs and Biologics

1. Estrogen Receptors
2. Hormones (Hormone)
3. Aromatase Inhibitors
4. Estrogens (Estrogen)
5. Anastrozole (Arimidex)
6. Letrozole (Femara)
7. Estrogen Receptor Modulators (Antiestrogen)
8. exemestane (Aromasin)
9. Selective Estrogen Receptor Modulators (SERM)
10. Raloxifene Hydrochloride (Evista)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Chemoprevention
4. Radiotherapy
5. Segmental Mastectomy (Lumpectomy)