Abstract | AIMS: METHODS AND RESULTS: A total of 305 consecutive patients with a first STEMI who underwent OCT imaging of culprit lesions during primary percutaneous coronary intervention (PCI) were prospectively enrolled. OCT findings of the culprit plaque were compared between patients with (n=206) and without PIA (n=99). Patients with PIA showed lower rates of thin-cap fibroatheroma (TCFA) (62.6% vs. 80.8%, p=0.001) and plaque rupture (56.8% vs. 72.7%, p=0.007), smaller maximum ruptured cavity areas (1.10±1.04 mm2 vs. 1.53±1.20 mm2, p=0.002), and more severe residual luminal narrowing (p=0.015) with a higher incidence of white residual thrombus (68.4% vs. 50.0%, p=0.003) at the culprit lesions than patients without PIA. No significant differences in clinical outcomes were observed at the one-year follow-up. CONCLUSIONS: In patients with a first STEMI, PIA was significantly associated with a lower incidence of TCFA and plaque rupture, a smaller ruptured cavity area, more white residual thrombi, and more severe lumen stenosis at the culprit lesions.
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Authors | Rong Sun, Sining Hu, Giulio Guagliumi, Haibo Jia, Jinwei Tian, Lulu Li, Shaotao Zhang, Yini Wang, Shaosong Zhang, Jingbo Hou, Bo Yu |
Journal | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
(EuroIntervention)
Vol. 14
Issue 17
Pg. 1768-1775
(Apr 20 2019)
ISSN: 1969-6213 [Electronic] France |
PMID | 30277462
(Publication Type: Journal Article)
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Topics |
- Coronary Angiography
- Humans
- Infarction
- Myocardial Infarction
- Percutaneous Coronary Intervention
- Plaque, Atherosclerotic
- ST Elevation Myocardial Infarction
- Tomography, Optical Coherence
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