Excessive gestational weight gain in accordance with the IOM criteria and the risk of hypertensive disorders of pregnancy: a meta-analysis.

Abstract

BACKGROUND:

Excessive gestational weight gain (GWG) is a potential risk factor for hypertensive disorders of pregnancy (HDP).

METHODS:

We systematically reviewed three electronic databases for relevant articles published in English: PubMed, EMBASE and Web of Science. The Newcastle-Ottawa Scale was used to assess study quality. Random-effects meta-analyses were performed to supply a pooled estimation of the OR comparing the risk of HDP among healthy pregnant women with and without excessive GWG.

RESULTS:

The pooled estimation for the association between excessive GWG and the risk of HDPs yielded an odds ratio (OR) of 1.79 (95% CI: 1.61-1.99). A subgroup analysis showed that women who had excessive GWG were more likely to have an HDP (OR 1.82; 95% CI 1.53-2.17), preeclampsia (OR 1.92; 95% CI 1.36-2.72), or gestational hypertension (OR 1.67; 95% CI 1.43-1.95). The pooled estimation for the association between excessive GWG and the risk of HDPs among pregestational normal weight women yielded an OR of 1.57 (95% CI 1.26-1.96). A subgroup analysis showed that women who had excessive GWG were more likely to have HDP (OR 1.45; 95% CI 1.09-1.92) or gestational hypertension (OR 1.51; 95% CI 1.22-1.86). The summary ORs of pre-gestational underweight women and pre-gestational overweight and obese women were 2.17 (95% CI 1.56-3.02) and 1.32 (95% CI 1.08-1.63), respectively.

CONCLUSIONS:

The findings of this study suggest that excessive GWG in accordance with the IOM recommendations influences the rate of HDP.

• Authors: Min Ren, Hanying Li, Wei Cai, Xiulong Niu, Wenjie Ji, Zhuoli Zhang, Jianmin Niu, Xin Zhou, Yuming Li
• Journal: BMC pregnancy and childbirth (BMC Pregnancy Childbirth) Vol. 18 Issue 1 Pg. 281 (Jul 04 2018) ISSN: 1471-2393 [Electronic] England
• PMID: 29973178 (Publication Type: Journal Article, Meta-Analysis)

Topics

• Correlation of Data
• Female
• Gestational Weight Gain
• Humans
• Hypertension (diagnosis)
• Hypertension, Pregnancy-Induced (diagnosis)
• Pregnancy
• Pregnancy Complications, Cardiovascular (diagnosis)
• Risk Factors